Psychological factors such as depression, anxiety, fear and anger seem to have a greater impact than biomedical or biomechanical factors on Chronic Lower Back Pain disability.
In Chronic Lower Back Pain, the reduction in quality of life could be attributed to pain related sleep disturbances, fatigue, medication abuse functional disability and stress.
In patients with fibromyalgia and Chronic Lower Back Pain, the degree of pain, perceived disability and Quality of Life were influenced more by their mental health status than the degree of physical impairment.
Yoga, with its holistic approach to improve overall quality of life, offers several self regulatory practices that aim at correcting these psychological factors that contribute to low Quality of Life. An integrated approach to yoga therapy that includes practices at physical, breathing, mental, intellectual and emotional levels has been shown to be effective in improving the Quality of Life in several chronic conditions such as fibromyalgia, rheumatoid arthritis and cancer. 
Additionally, multidisciplinary biopsychosocial rehabilitation has been shown to be better than usual care in improving Quality of Life with reduction in pain and functional disability in patients with chronic back pain.
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