Medicine cannot, and should not, be practiced without up-to-date evidence. Nor can medicine be practiced without knowing and respecting the informed preferences of patients. Clinicians, researchers, teachers, and patients need to be aware of and actively facilitate the interdependent relationship of these approaches. Evidence-based medicine needs shared decision-making, and shared decision-making needs evidence-based medicine. Patients need both. http://ja.ma/1yy3ZYv